A M-ERA-NET project was awarded to a consortium including Gene2skin members RCSI and UMINHO together with the company IZERTIS. The project will focus on devising a bioprinting strategy to improve skin healing by targeting the wound biomechanic and associated signalling pathways.
UMINHO staff member Alexandra P. Marques was invited to speak at Jornadas de Biologia Aplicada 2016, a series of talks organized by final year students of the Applied Biology course of the University of Minho. The talk was about the work being done by UMINHO in the field of skin regeneration and the obstacles facing young researchers in the scientific career.
Gene2Skin Conference was held In Guimarães last October
First Gene2Skin Progress Meeting was held at KCL
Recent Awards by The Consortium
Selected Publications by The Consortium
One of the most devastating skin diseases, epidermolysis bullosa, is a genetic disease without cure and with too many variants yet to be fully understood. In Portugal there are around 84 registered cases, and 63% of patients have been diagnosed with a moderate to severe type. Considering that Gene2skin aims to fulfil the gap that UMINHO has regarding systems to perform genetic engineering and/or gene therapy and improve the knowledge on cellular and molecular mechanisms associated to skin diseases, UMINHO have contact Portuguese branch of DEBRA, an international Epidermolysis Bullosa (EB) patient support group in order to understand how skin regeneration strategies can help patients suffering from the disease.
The recent awarding to Alexandra P. Maruqes from the University of Minho was featured on several national news outlets: http://expresso.sapo.pt/sociedade/2016-12-13-Cinco-cientistas-ganham-bolsas-milionarias-do-Conselho-Europeu-de-Investigacao
UMINHO members of Gene2Skin Project participated in CHEM2NATURE first school. CHEM2NATURE is also a Twinning Project and as its main focus is in a different area from Gene2Skin, it is capable of complementing the scientific objectives of the current project.
UMINHO participated in IFATS meeting, which is a conference attended mostly by plastic surgeons and therefore it was highly relevant to present the work that is being carried out to this community. The work that was presented in the three oral communications referred to the use adipose tissue as a source of cells for skin regenerative purposes focusing on the control of the cell signalling, as envisaged by Gene2Skin.
UMINHO participated in this is a heavily industry-driven meeting, where they were able to interact with several research-based companies and understand better the path from the bench to a marketable product.
2016 Gene2Skin conference (Guimarães, Portugal) that was organized back-to-back with the TERMSTEM meeting that is traditionally a more industry-driven meeting. Among the companies invited were Novadip (Belgium), Poietis (France) and Cytograft (US) whose focus coincides with the scientific strategy of UMINHO in the scope of Gene2skin.
Chronic wounds and in particular diabetic foot ulcers have terrible consequences in the quality of life of patients and significantly high mortality associated. It is also a concern of Gene2Skin Project the progress in chronic wounds research towards regeneration. The Portuguese Association of Podiatrists determination and clinical practice in different local hospitals in the Diabetic Foot Ulceration, offers a well-integrated vision of the treatments in this field.